Investigation was carried out at the National Horticultural Research Institute(NIHORT), Ibadan, Nigeria on the effects of cutting height and shoots harvesting frequency on the yield of Solanum marcrocarpon. The experiment was a 2 x 3 factorial fitted into RCBD in three replications. Plants were transplanted at 50 x 50cm into the field after four weeks in the nursery, at three intervals of two, three and four weeks. Shoots were cut at 10cm and 20 cm above ground. Result showed that cumulative shoot yield per m2 was significantly higher when the crop was harvested at 10cm x 2 weeks interval and least at 20cm x 4 weeks. In all cases, there was no significant difference in yield per m2 during the third and fourth harvest. Cumulative yield ha-1 was not significantly differentiate 10cm x 2 weeks and 20cm x 2weeks but different from the other treatments. Considering management of resources, harvest by cutting of shoots at 10cm or 20cm high at 2 weeks is recommended.