Chemical control of soil borne diseases of tomato is seldom successful or cost effective and not a safe option for disease control. Field studies were therefore conducted for two years (2005 and 2006) in Ibadan, Nigeria to evaluate the disease potential of trykocide, a biological formulation. Results showed better control of Sclerotium wilt incidence than bacterial wilt incident induced by Sclerotium rolfsii and Ralstonia solanacearum respectively in tomato. Trykocide applied at 12 l/ha at both years significantly improved seedling establishment. Also, the application of trykocide at 12 l/ha reduced significantly incidence of Sclerotium wilt. Trykocide at 6 l/ha significantly improved the vegetative growth of tomato plants with resultant higher yields. Alternative approaches (non chemical) for the management of soil borne disease of tomato are identified.